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Compute Iterative Correction (Vanilla Count) on hic maps.

Usage

ICEnorm(hic, qtlTh = 0.15, maxIter = 50)

Arguments

hic

: The HiC maps chunk to normalize.

qtlTh

: The threshold quantile below which the bins will be ignored. (Default 0.15)

maxIter

: The maximum iteration number.

Value

A normalized contactMatrix

Details

ICEnorm

Examples

data(HiC_Ctrl.cmx_lst)
HiC_Ctrl_ICE.cmx <- ICEnorm(HiC_Ctrl.cmx_lst[['2L_2L']])